Grazzia Rey

University of the Republic, Uruguay

Title: The first 1000 days of life, The developmental origins of health and disease

Abstract

Objective: To evaluate the placental histological findings in preterm and early terms in the Maternity Unit at the University Hospital.

Materials and methods: Descriptive observational prospective study in the period August 2015-February 2016. The inclusion criteria were births between 22 and 38 weeks 6/7 days and exclusion criteria twin pregnancy and fetal malformations. The placentas were sent to pathological anatomy with prior consent, approved by the Hospital Ethics Committee. The histological findings analyzed were: elements of poor maternal perfusion, chronic villi, inflammation and acute infection and fetal vascular thrombosis, correlating them with gestational age. The results were expressed as an average, for discrete variables the number of cases and relative frequency were used. According to the type of variables, Student's t test and chi-square with Fisher's correction for small samples were used.

Results: 410 births were registered in that period of time, of which 235 were terms, 130 early terms and 45 preterms. The main histopathological finding was poor maternal vascular perfusion. Among other findings, we highlight 40% of immature placentas in early terms.

Conclusion: The most frequent histopathological finding was poor maternal vascular perfusion in both populations evaluated, probably due to the type of maternity with high medical obstetric risk. Knowledge of placental pathologies can guide towards the etiology of prematurity and its classification, as well as helping the new-born’s decision-making and future planning for another pregnancy

Biography

Dr. Grazzia Rey has been working at the University of the Republic since she was 21 years old in different departments of the Faculty of Medicine, currently she is working as an associate professor of the gynecological clinic B at the Hospital de Clínicas and she is also a researcher with a special interest in innovations at the level of medical informatics.

4th International Conference on Nursing and Women's Healthcare

Grazzia Rey

Title: The first 1000 days of life, The developmental origins of health and disease

Abstract

Biography

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