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Hendriketa da Silva
The National University of East Timor, Timor-LestePresentation Title:
Molecular epidemiology of HBV based on subtipy angenotipy in Timor-Leste
Abstract
Background: Hepatitis B virus (HBV) infection remains a serious health problem in Timor-Leste, however data on its prevalence is still very limited. According to some reports, the prevalence of HBsAg in general population in Timor-Leste ranges from 6.9% to 12.4%. Previous research on blood donors in the city of Dili also indicated the biodiversity of the HBV genotype and HBsAg subtype.
Aim: This study aimed to elucidate the recent mapping out the distribution of HBV genotypes and HBsAg subtypes in the general population in Timor-Leste.
Method: This study was conducted using a cross sectional design to analyze HBV genotype distributions and HBsAg subtypes.
Results: The results revealed that 69 of 683 subjects from six Municipalities (Districts) in Timor Leste were HBsAg positives. genotype C was predominant (72.8%), followed by genotype B (25.7%) and genotype A (1.5%). All of the main HBsAg subtypes were found in Timor-Leste i.e. adr subtype (71.2%), followed by ayw subtype (24.2%), adw subtype (3,1%), and ayr subtype (1.5%).
Conclusions: It was concluded that sub genotype C2 and subtype adr were predominant.
Biography
Hendriketa da Silva is a Senior lecturer and
director of Master degree of Medicine Tropical and Community Health at the
University of National Timor-Lorosa'e at the Faculty of Medical Sciences and
Postgraduation. researchers with a bachelor's degree in laboratory Medicine from
Dr. Soetomo University in Indonesia, a master of public health from Gadja Mada
University, Yogyakarta and Doctors from Udayana University, Bali, Indonesia.
She have done ten research International publications and have been working in
the field of laboratory and public Health for 20 years. She has completed
doctor for 3.5 years